Adaptive optics correct for the blurring effects of the Earth’s atmosphere. However, most AO systems today suffer from limited fields of view and point spread functions that vary over time and position. I will present results from several experiments to overcome these limitations. We have deployed a ground-layer adaptive optics experiment on the UH 2.2 m telescope on Maunakea to test the AO image quality over fields of view as large as 20 arcminutes. This experiment is a key first step in understanding whether a GLAO system would be feasible for other 8-10 m telescopes equipped with wide-field multi-object spectrographs. We are currently investigating the science feasibility of such a system for Keck. I will also present our efforts to reconstruct the AO point spread function and deliver more precise scientific measurements from Keck’s narrow-field AO system. Initial science applications include close binaries, quasar host galaxies, and the Galactic Center. Future cases include strongly lensed galaxies and supernovae, black hole hunting with astrometric microlensing, and direct imaging of exoplanets.